14-P003 Identification of genes expressed in the anterior definitive endoderm
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منابع مشابه
14-P003 Identification of genes expressed in the anterior definitive endoderm
The enteric nervous system (ENS) derives from neural crest, which invade and migrate along the developing gut, proliferate extensively, and differentiate into neurons and glial cells organized as interconnected ganglia that control complex behaviours of the gut, such as peristalsis. While most ENS progenitors undergo differentiation, cells exhibiting properties of enteric progenitor cells (EPCs...
متن کاملIdentification and functional analysis of novel genes expressed in the Anterior Visceral Endoderm.
During early vertebrate development, the correct establishment of the body axes is critical. The anterior pole of the mouse embryo is established when Distal Visceral Endoderm (DVE) cells migrate to form the Anterior Visceral Endoderm (AVE). Symmetrical expression of Lefty1, Cer1 and Dkk1 determines the direction of DVE migration and the future anterior side. In addition to the establishment of...
متن کاملAnterior identity is established in chick epiblast by hypoblast and anterior definitive endoderm.
Previous studies of head induction in the chick have failed to demonstrate a clear role for the hypoblast and anterior definitive endoderm (ADE) in patterning the overlying ectoderm, whereas data from both mouse and rabbit suggest patterning roles for anterior visceral endoderm (AVE) and ADE. Based on similarity of gene expression patterns, fate and a dual role in 'protecting' the prospective f...
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The use of embryonic stem cell (ESC) differentiation to generate functional hepatic or pancreatic progenitors and as a tool for developmental biology is limited by an inability to isolate in vitro equivalents of regionally specified anterior definitive endoderm (ADE). To address this, we devised a strategy using a fluorescent reporter gene under the transcriptional control of the anterior endod...
متن کاملstauprimide priming of human embryonic stem cells toward definitive endoderm
objective: in vitro production of a definitive endoderm (de) is an important issue in stem cell-related differentiation studies and it can assist with the production of more efficient endoderm derivatives for therapeutic applications. despite tremendous progress in de differentiation of human embryonic stem cells (hescs), researchers have yet to discover universal, efficient and cost-effective ...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2009
ISSN: 0925-4773
DOI: 10.1016/j.mod.2009.06.622